clinPK-package | clinPK |

add_ruv | Add residual variability to data |

as.num | factors or characters to numeric |

auc2dose | Convert AUCtau or AUCt to dose (for 1-compartment linear PK model) |

calc_abw | Calculate adjusted body weight (ABW) |

calc_amts_for_conc | Calculate the amounts in all compartments in a compartmental PK system based on a given concentration in the central compartment, and assuming steady state. |

calc_bmi | Calculate BMI |

calc_bsa | Calculate body surface area |

calc_creat | Estimate serum creatinine |

calc_creat_neo | Estimate serum creatinine in neonates |

calc_egfr | Calculate eGFR |

calc_egfr_cystatin | Calculate eGFR based on Cystatin C measurements |

calc_ffm | Calculate fat-free mass |

calc_ibw | Calculate ideal body weight for children and adults |

calc_kel_single_tdm | Calculate elimination rate when given a single TDM sample |

calc_lbw | Calculate lean body weight |

calc_t12 | Calculate half-life based on two points |

cm2inch | Convert cm to inch |

conc2mol | Convert concentration to molar |

convert_creat_assay | Convert serum creatinine from various assays to Jaffe |

convert_creat_unit | Convert creatinine to different unit |

dose2auc | Convert dose to expected AUCinf or AUCt for 1 compartment linear PK model |

find_nearest_dose | Generic function to calculate the dose nearest to a specific dose unit increment |

find_nearest_interval | Generic function to calculate the interval nearest to a possible dosing interval |

inch2cm | Convert inch to cm |

is.nil | Check if values in vector are empty |

kg2lbs | Convert kg to lbs |

lbs2kg | Convert lbs to kg |

mol2conc | Convert molar to concentration |

nca | Perform an NCA based on a NONMEM-style dataset |

pct_bmi_for_age | Percentile BMI for age for children |

pct_for_age_generic | Percentile height or weight for age for children |

pct_height_for_age | Percentile height for age for children |

pct_weight_for_age | Percentile weight for age for children |

pk_1cmt_bolus | Concentration predictions for 1-compartmental PK model after single or multiple bolus doses |

pk_1cmt_bolus_cmax_ss | Cmax for linear 1-compartment PK model at steady state, bolus dosing |

pk_1cmt_bolus_cmin_ss | Cmin (trough) for linear 1-compartment PK model at steady state, bolus dosing |

pk_1cmt_bolus_dose_from_cmax | Calculate dose to achieve steady state Cmax for 1-compartmental PK model bolus dosing at steady state |

pk_1cmt_bolus_dose_from_cmin | Calculate dose to achieve steady state trough for 1-compartmental PK model bolus dosing at steady state |

pk_1cmt_bolus_ss | Concentration predictions for 1-compartmental PK model with bolus dosing at steady state |

pk_1cmt_inf | Concentration predictions for 1-compartmental PK model after single or multiple bolus doses |

pk_1cmt_inf_cmax_ss | Cmax for linear 1-compartment PK model at steady state |

pk_1cmt_inf_cmin_ss | Cmin (trough) for linear 1-compartment PK model at steady state |

pk_1cmt_inf_dose_from_cmax | Calculate dose to achieve steady state Cmax for 1-compartmental PK model with infusion dosing at steady state |

pk_1cmt_inf_dose_from_cmin | Calculate dose to achieve steady state trough for 1-compartmental PK model with infusion dosing at steady state |

pk_1cmt_inf_ss | Concentration predictions for 2-compartmental PK model with infusion dosing at steady state |

pk_1cmt_oral | Concentration predictions for 1-compartmental oral PK model after single or multiple bolus doses |

pk_1cmt_t12 | Calculate terminal half-life for 1-compartment model |

pk_2cmt_bolus | Concentration predictions for 1-compartmental PK model, single or multiple bolus doses |

pk_2cmt_bolus_cmax_ss | Cmax for 2-compartmental PK model, bolus dosing at steady state |

pk_2cmt_bolus_cmin_ss | Cmin (trough) for 2-compartmental PK model, bolus dosing at steady state |

pk_2cmt_bolus_dose_from_cmax | Calculate dose to achieve steady state Cmax for 2-compartmental PK model bolus dosing at steady state |

pk_2cmt_bolus_dose_from_cmin | Calculate dose to achieve steady state trough for 2-compartmental PK model bolus dosing at steady state |

pk_2cmt_bolus_ss | Concentration predictions for 2-compartmental PK model, bolus dosing at steady state |

pk_2cmt_inf | Concentration predictions for 1-compartmental PK model, single or multiple infusions |

pk_2cmt_inf_cmax_ss | Cmax (trough) for 2-compartmental PK model, bolus dosing at steady state |

pk_2cmt_inf_cmin_ss | Cmin (trough) for 2-compartmental PK model, bolus dosing at steady state |

pk_2cmt_inf_dose_from_cmax | Calculate dose to achieve steady state Cmax for 2-compartmental PK model with infusion dosing at steady state |

pk_2cmt_inf_dose_from_cmin | Calculate dose to achieve steady state trough for 2-compartmental PK model with infusion dosing at steady state |

pk_2cmt_inf_ss | Concentration predictions for 1-compartmental PK model with infusion dosing at steady state |

pk_2cmt_t12 | Calculate half-life(s) for 2-compartment model |

pk_2cmt_t12_interval | Calculate average half-life for 2-compartment model during a specific interval |

read_who_table | Internal function to read WHO growth tables from package or download from WHO |

weight2kg | Convert any weight unit to kg |