pk_2cmt_inf_ss {clinPK} | R Documentation |
Concentration predictions for 1-compartmental PK model with infusion dosing at steady state
pk_2cmt_inf_ss(t = c(0:24), dose = 100, t_inf = 1, tau = 12, CL = 3, V = 30, Q = 2, V2 = 20, ruv = NULL)
t |
vector of time |
dose |
dose |
t_inf |
infusion time |
tau |
dosing interval |
CL |
clearance |
V |
volume of distribution |
Q |
inter-compartimental clearance |
V2 |
volume of peripheral compartment |
ruv |
residual variability, specified as list with optional arguments for proportional, additive, or exponential components, e.g. 'list(prop=0.1, add=1, exp=0)' |
pk_2cmt_inf_ss( dose = 1000, tau = 12, t_inf = 2, CL = 5, V = 50, Q = 20, V2 = 200)