pk_2cmt_bolus {clinPK}

Concentration predictions for 2-compartmental PK model, single or multiple bolus doses

Description

Concentration predictions for 2-compartmental PK model, single or multiple bolus doses

Usage

pk_2cmt_bolus(
  t = c(0:24),
  dose = 100,
  tau = 12,
  CL = 3,
  V = 30,
  Q = 2,
  V2 = 20,
  ruv = NULL
)

Arguments

t

vector of time

dose

dose

tau

dosing interval

CL

clearance

V

volume of central compartment

Q

inter-compartimental clearance

V2

volume of peripheral compartment

ruv

residual error (list)

Examples

pk_2cmt_bolus(dose = 1000, tau = 24, CL = 5, V = 50, Q = 15, V2 = 200)