pk_2cmt_inf_dose_from_cmin {clinPK} | R Documentation |

## Calculate dose to achieve steady state trough for 2-compartmental PK model with infusion dosing at steady state

### Description

Calculate dose to achieve steady state trough for 2-compartmental PK model with infusion dosing at steady state

### Usage

```
pk_2cmt_inf_dose_from_cmin(
cmin = 1,
tau = 12,
t_inf = 1,
CL = 3,
V = 30,
Q = 2,
V2 = 20
)
```

### Arguments

`cmin` |
desired trough concentration |

`tau` |
dosing interval |

`t_inf` |
infusion time |

`CL` |
clearance |

`V` |
volume of distribution |

`Q` |
inter-compartimental clearance |

`V2` |
volume of peripheral compartment |

### Examples

```
dos <- pk_2cmt_inf_dose_from_cmin(
cmin = 10, tau = 12, t_inf = 2,
CL = 5, V = 50, Q = 20, V2 = 200)
find_nearest_dose(dos, 100)
```

[Package

*clinPK*version 0.13.0 Index]