pk_1cmt_inf_ss {clinPK}

Concentration predictions for 2-compartmental PK model with infusion dosing at steady state

Description

Concentration predictions for 2-compartmental PK model with infusion dosing at steady state

Usage

pk_1cmt_inf_ss(
  t = c(0:24),
  dose = 100,
  t_inf = 1,
  tau = 12,
  CL = 3,
  V = 30,
  ruv = NULL
)

Arguments

t

vector of time

dose

dose

t_inf

infusion time

tau

dosing interval

CL

clearance

V

volume of distribution

ruv

residual variability, specified as list with optional arguments for proportional, additive, or exponential components, e.g. 'list(prop=0.1, add=1, exp=0)'

Examples

pk_1cmt_inf_ss(dose = 500, tau = 12, t_inf = 2, CL = 5, V = 50)
pk_1cmt_inf_ss(
  dose = 500, tau = 12, t_inf = 2, CL = 5, V = 50,
  ruv = list(prop = 0.1, add = 0.1))