Interface to the 'Pharmpy' 'Pharmacometrics' Library


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Documentation for package ‘pharmr’ version 1.0.1

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A B C D E F G H I L M O P R S T U W

-- A --

add_admid add_admid
add_allometry add_allometry
add_bioavailability add_bioavailability
add_cmt add_cmt
add_covariate_effect add_covariate_effect
add_derivative add_derivative
add_effect_compartment add_effect_compartment
add_estimation_step add_estimation_step
add_iiv add_iiv
add_indirect_effect add_indirect_effect
add_individual_parameter add_individual_parameter
add_iov add_iov
add_lag_time add_lag_time
add_metabolite add_metabolite
add_parameter_uncertainty_step add_parameter_uncertainty_step
add_pd_iiv add_pd_iiv
add_peripheral_compartment add_peripheral_compartment
add_pk_iiv add_pk_iiv
add_population_parameter add_population_parameter
add_predictions add_predictions
add_residuals add_residuals
add_time_after_dose add_time_after_dose
append_estimation_step_options append_estimation_step_options

-- B --

bin_observations bin_observations
bump_model_number bump_model_number

-- C --

calculate_aic calculate_aic
calculate_bic calculate_bic
calculate_corr_from_cov calculate_corr_from_cov
calculate_corr_from_prec calculate_corr_from_prec
calculate_cov_from_corrse calculate_cov_from_corrse
calculate_cov_from_prec calculate_cov_from_prec
calculate_epsilon_gradient_expression calculate_epsilon_gradient_expression
calculate_eta_gradient_expression calculate_eta_gradient_expression
calculate_eta_shrinkage calculate_eta_shrinkage
calculate_individual_parameter_statistics calculate_individual_parameter_statistics
calculate_individual_shrinkage calculate_individual_shrinkage
calculate_parameters_from_ucp calculate_parameters_from_ucp
calculate_pk_parameters_statistics calculate_pk_parameters_statistics
calculate_prec_from_corrse calculate_prec_from_corrse
calculate_prec_from_cov calculate_prec_from_cov
calculate_se_from_cov calculate_se_from_cov
calculate_se_from_prec calculate_se_from_prec
calculate_ucp_scale calculate_ucp_scale
check_dataset check_dataset
check_high_correlations check_high_correlations
check_parameters_near_bounds check_parameters_near_bounds
check_pharmpy Checks version of Pharmpy/pharmr
cleanup_model cleanup_model
convert_model convert_model
create_basic_pk_model create_basic_pk_model
create_config_template create_config_template
create_joint_distribution create_joint_distribution
create_report create_report
create_rng create_rng
create_symbol create_symbol

-- D --

deidentify_data deidentify_data
display_odes display_odes
drop_columns drop_columns
drop_dropped_columns drop_dropped_columns

-- E --

evaluate_epsilon_gradient evaluate_epsilon_gradient
evaluate_eta_gradient evaluate_eta_gradient
evaluate_expression evaluate_expression
evaluate_individual_prediction evaluate_individual_prediction
evaluate_population_prediction evaluate_population_prediction
evaluate_weighted_residuals evaluate_weighted_residuals
expand_additional_doses expand_additional_doses

-- F --

filter_dataset filter_dataset
find_clearance_parameters find_clearance_parameters
find_volume_parameters find_volume_parameters
fit fit
fix_or_unfix_parameters fix_or_unfix_parameters
fix_parameters fix_parameters
fix_parameters_to fix_parameters_to

-- G --

get_admid get_admid
get_baselines get_baselines
get_bioavailability get_bioavailability
get_central_volume_and_clearance get_central_volume_and_clearance
get_cmt get_cmt
get_concentration_parameters_from_data get_concentration_parameters_from_data
get_config_path get_config_path
get_covariate_baselines get_covariate_baselines
get_covariate_effects get_covariate_effects
get_doseid get_doseid
get_doses get_doses
get_dv_symbol get_dv_symbol
get_evid get_evid
get_ids get_ids
get_individual_parameters get_individual_parameters
get_individual_prediction_expression get_individual_prediction_expression
get_initial_conditions get_initial_conditions
get_lag_times get_lag_times
get_mdv get_mdv
get_model_code get_model_code
get_model_covariates get_model_covariates
get_number_of_individuals get_number_of_individuals
get_number_of_observations get_number_of_observations
get_number_of_observations_per_individual get_number_of_observations_per_individual
get_number_of_peripheral_compartments get_number_of_peripheral_compartments
get_number_of_transit_compartments get_number_of_transit_compartments
get_observations get_observations
get_observation_expression get_observation_expression
get_omegas get_omegas
get_parameter_rv get_parameter_rv
get_pd_parameters get_pd_parameters
get_pk_parameters get_pk_parameters
get_population_prediction_expression get_population_prediction_expression
get_rv_parameters get_rv_parameters
get_sigmas get_sigmas
get_thetas get_thetas
get_unit_of get_unit_of
get_zero_order_inputs get_zero_order_inputs
greekify_model greekify_model

-- H --

has_additive_error_model has_additive_error_model
has_combined_error_model has_combined_error_model
has_covariate_effect has_covariate_effect
has_first_order_absorption has_first_order_absorption
has_first_order_elimination has_first_order_elimination
has_instantaneous_absorption has_instantaneous_absorption
has_linear_odes has_linear_odes
has_linear_odes_with_real_eigenvalues has_linear_odes_with_real_eigenvalues
has_michaelis_menten_elimination has_michaelis_menten_elimination
has_mixed_mm_fo_elimination has_mixed_mm_fo_elimination
has_odes has_odes
has_presystemic_metabolite has_presystemic_metabolite
has_proportional_error_model has_proportional_error_model
has_random_effect has_random_effect
has_seq_zo_fo_absorption has_seq_zo_fo_absorption
has_weighted_error_model has_weighted_error_model
has_zero_order_absorption has_zero_order_absorption
has_zero_order_elimination has_zero_order_elimination

-- I --

install_pharmpy Install Pharmpy
install_pharmpy_devel Install Pharmpy (with specified version)
is_linearized is_linearized
is_real is_real
is_strictness_fulfilled is_strictness_fulfilled

-- L --

list_time_varying_covariates list_time_varying_covariates
load_dataset load_dataset
load_example_model load_example_model
load_example_modelfit_results load_example_modelfit_results

-- M --

make_declarative make_declarative
mu_reference_model mu_reference_model

-- O --

omit_data omit_data

-- P --

plot_abs_cwres_vs_ipred plot_abs_cwres_vs_ipred
plot_cwres_vs_idv plot_cwres_vs_idv
plot_dv_vs_ipred plot_dv_vs_ipred
plot_dv_vs_pred plot_dv_vs_pred
plot_eta_distributions plot_eta_distributions
plot_individual_predictions plot_individual_predictions
plot_iofv_vs_iofv plot_iofv_vs_iofv
plot_transformed_eta_distributions plot_transformed_eta_distributions
plot_vpc plot_vpc
predict_influential_individuals predict_influential_individuals
predict_influential_outliers predict_influential_outliers
predict_outliers predict_outliers
print_fit_summary print_fit_summary
print_model_code print_model_code
print_model_symbols print_model_symbols
print_pharmpy_version Print pharmpy version

-- R --

read_dataset_from_datainfo read_dataset_from_datainfo
read_model read_model
read_modelfit_results read_modelfit_results
read_model_from_string read_model_from_string
read_results read_results
remove_bioavailability remove_bioavailability
remove_covariate_effect remove_covariate_effect
remove_derivative remove_derivative
remove_error_model remove_error_model
remove_estimation_step remove_estimation_step
remove_iiv remove_iiv
remove_iov remove_iov
remove_lag_time remove_lag_time
remove_loq_data remove_loq_data
remove_parameter_uncertainty_step remove_parameter_uncertainty_step
remove_peripheral_compartment remove_peripheral_compartment
remove_predictions remove_predictions
remove_residuals remove_residuals
remove_unused_parameters_and_rvs remove_unused_parameters_and_rvs
rename_symbols rename_symbols
replace_non_random_rvs replace_non_random_rvs
resample_data resample_data
reset_index Reset index
reset_indices_results Reset result indices
retrieve_models retrieve_models
run_allometry run_allometry
run_amd run_amd
run_bootstrap run_bootstrap
run_covsearch run_covsearch
run_estmethod run_estmethod
run_iivsearch run_iivsearch
run_iovsearch run_iovsearch
run_linearize run_linearize
run_modelfit run_modelfit
run_modelsearch run_modelsearch
run_retries run_retries
run_ruvsearch run_ruvsearch
run_simulation run_simulation
run_structsearch run_structsearch
run_tool run_tool

-- S --

sample_individual_estimates sample_individual_estimates
sample_parameters_from_covariance_matrix sample_parameters_from_covariance_matrix
sample_parameters_uniformly sample_parameters_uniformly
set_additive_error_model set_additive_error_model
set_baseline_effect set_baseline_effect
set_combined_error_model set_combined_error_model
set_covariates set_covariates
set_dataset set_dataset
set_direct_effect set_direct_effect
set_dtbs_error_model set_dtbs_error_model
set_dvid set_dvid
set_estimation_step set_estimation_step
set_evaluation_step set_evaluation_step
set_first_order_absorption set_first_order_absorption
set_first_order_elimination set_first_order_elimination
set_iiv_on_ruv set_iiv_on_ruv
set_initial_condition set_initial_condition
set_initial_estimates set_initial_estimates
set_instantaneous_absorption set_instantaneous_absorption
set_lloq_data set_lloq_data
set_lower_bounds set_lower_bounds
set_michaelis_menten_elimination set_michaelis_menten_elimination
set_mixed_mm_fo_elimination set_mixed_mm_fo_elimination
set_name set_name
set_ode_solver set_ode_solver
set_peripheral_compartments set_peripheral_compartments
set_power_on_ruv set_power_on_ruv
set_proportional_error_model set_proportional_error_model
set_reference_values set_reference_values
set_seq_zo_fo_absorption set_seq_zo_fo_absorption
set_simulation set_simulation
set_time_varying_error_model set_time_varying_error_model
set_tmdd set_tmdd
set_transit_compartments set_transit_compartments
set_upper_bounds set_upper_bounds
set_weighted_error_model set_weighted_error_model
set_zero_order_absorption set_zero_order_absorption
set_zero_order_elimination set_zero_order_elimination
set_zero_order_input set_zero_order_input
simplify_expression simplify_expression
solve_ode_system solve_ode_system
split_joint_distribution split_joint_distribution
summarize_modelfit_results summarize_modelfit_results

-- T --

transform_blq transform_blq
transform_etas_boxcox transform_etas_boxcox
transform_etas_john_draper transform_etas_john_draper
transform_etas_tdist transform_etas_tdist
translate_nmtran_time translate_nmtran_time

-- U --

unconstrain_parameters unconstrain_parameters
undrop_columns undrop_columns
unfix_parameters unfix_parameters
unfix_parameters_to unfix_parameters_to
unload_dataset unload_dataset
update_initial_individual_estimates update_initial_individual_estimates
use_thetas_for_error_stdev use_thetas_for_error_stdev

-- W --

write_csv write_csv
write_model write_model
write_results write_results