set_initial_estimates {pharmr}

set_initial_estimates

Description

Update initial parameter estimate for a model

Updates initial estimates of population parameters for a model. If the new initial estimates are out of bounds or NaN this function will raise.

Usage

set_initial_estimates(model, inits, move_est_close_to_bounds = FALSE)

Arguments

model

(Model) Pharmpy model to update initial estimates

inits

(list(str=numeric)) Initial parameter estimates to update

move_est_close_to_bounds

(logical) Move estimates that are close to bounds. If correlation >0.99 the correlation will be set to 0.9, if variance is <0.001 the variance will be set to 0.01.

Value

(Model) Pharmpy model object

See Also

fix_parameters_to : Fixing and setting parameter initial estimates in the same function

unfix_paramaters_to : Unfixing parameters and setting a new initial estimate in the same

Examples

## Not run: 
model <- load_example_model("pheno")
results <- load_example_modelfit_results("pheno")
model$parameters$inits
model <- set_initial_estimates(model, results$parameter_estimates)
model$parameters$inits
model <- load_example_model("pheno")
model <- set_initial_estimates(model, {'POP_CL': 2.0})
model$parameters['POP_CL']

## End(Not run)