calculate_individual_shrinkage {pharmr}

calculate_individual_shrinkage

Description

Calculate the individual eta-shrinkage

Definition: ieta_shr = (var(eta) / omega)

Usage

calculate_individual_shrinkage(
  model,
  parameter_estimates,
  individual_estimates_covariance
)

Arguments

model

(Model) Pharmpy model

parameter_estimates

(array) Parameter estimates of model

individual_estimates_covariance

(data.frame) Uncertainty covariance matrices of individual estimates

Value

(DataFrame) Shrinkage for each eta and individual

See Also

calculate_eta_shrinkage

Examples

## Not run: 
model <- load_example_model("pheno")
results <- load_example_modelfit_results("pheno")
pe <- results$parameter_estimates
covs <- results$individual_estimates_covariance
calculate_individual_shrinkage(model, pe, covs)

## End(Not run)