Escalation with Overdose Control


[Up] [Top]

Documentation for package ‘ewoc’ version 0.3.0

Help Pages

accuracy_index Accuracy Index
average_toxicity Average Toxicity Number
dlt_curve_d1classical Plot the DLT curve based on the EWOC classical model
dlt_curve_d1extended Plot the DLT curve based on the EWOC extended model
dlt_curve_d1ph Plot the DLT curve based on the EWOC proportional hazards model
dlt_rate Evaluation of the DLT rate
ewoc_d1classical Escalation With Overdose Control
ewoc_d1extended Escalation With Overdose Control
ewoc_d1ph Escalation With Overdose Control
ewoc_simulation EWOC simulation
inv_standard_dose Inverse standardization of the dose
logit Logit
mtd_bias Bias of the MTD estimates
mtd_mse Mean Square Error of the MTD estimates
mtd_rho_d1extended Convert mtd to rho_1 and vice-versa
opc Operating characteristics for EWOC simulations
optimal_mtd Percent of doses in relation the optimal MTD interval
optimal_toxicity Percent of doses in relation the optimal toxicity interval
pdlt_d1classical Generating a probability of DLT function based on the EWOC classical model
pdlt_d1extended Generating a probability of DLT function based on the EWOC extended model
pdlt_d1ph Generating a probability of DLT function based on the EWOC Proportional Hazards model
response_d1classical Generating a binary response function based on the EWOC classical model
response_d1extended Generating a binary response function based on the EWOC extended model
response_d1ph Generating a response function based on the EWOC Proportional Hazards model
standard_dose Standardization of the dose
stop_rule Evaluation of the stopping rule
stop_rule_d1classical Generating a stop rule function for EWOC classical model
stop_rule_d1extended Generating a stop rule function for EWOC extended model
stop_rule_d1ph Generating a stop rule function for EWOC proportional hazards model