stop_rule_d1ph {ewoc} | R Documentation |
Generating a stop rule function for EWOC proportional hazards model
Description
Generating a stop rule function for EWOC proportional hazards model
Usage
stop_rule_d1ph(step)
Arguments
step |
an object from the class 'ewoc_d1ph'. |
Details
The stop rule function is evaluated at each step of the trial. It can defined based on any information contained in the object 'step' that is the output from one of the functions 'ewoc_d1ph'.
Value
a logical character indicating if the trial should be stopped or not.
Examples
## Not run:
time <- 9
status <- 0
dose <- 20
step_zero <- ewoc_d1ph(cbind(time, status) ~ dose, type = 'discrete',
theta = 0.33, alpha = 0.25, tau = 10,
min_dose = 20, max_dose = 100,
dose_set = seq(20, 100, 20),
rho_prior = matrix(1, ncol = 2, nrow = 1),
mtd_prior = matrix(1, ncol = 2, nrow = 1),
distribution = 'exponential',
rounding = 'nearest')
stop_rule_d1ph(step_zero)
response_sim <- response_d1ph(rho = 0.05, mtd = 20, theta = 0.33,
min_dose = 10, max_dose = 50,
tau = 10, distribution = "exponential")
sim <- ewoc_simulation(step_zero = step_zero,
n_sim = 2, sample_size = 30,
alpha_strategy = "conditional",
response_sim = response_sim,
stop_rule_sim = stop_rule_d1ph,
ncores = 1)
## End(Not run)
[Package ewoc version 0.3.0 Index]