Bayesian Logistic Regression for Oncology Dose-Escalation Trials


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Documentation for package ‘OncoBayes2’ version 0.8-9

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bind_rows_0 Bind rows of multiple data frames with zero fill
blrm_exnex Bayesian Logistic Regression Model for N-compounds with EXNEX
blrm_formula_linear Build a BLRM formula with linear interaction term in logit-space
blrm_formula_saturating Build a BLRM formula with saturating interaction term in logit-space
blrm_trial Dose-Escalation Trials guided by Bayesian Logistic Regression Model
codata_combo2 Dataset: historical and concurrent data on a two-way combination
critical_quantile Critical quantile
critical_quantile.blrmfit Critical quantile
critical_quantile.blrm_trial Critical quantile
diagnostic-quantities Extract Diagnostic Quantities of 'OncoBayes2' Models
dose_info_combo2 Dataset: trial dose information for a dual-agent combination study
drug_info_combo2 Dataset: drug information for a dual-agent combination study
example-combo2 Two-drug combination example
example-combo2_trial Two-drug combination example using BLRM Trial
example-combo3 Three-drug combination example
example-single-agent Single Agent Example
example_model Runs example models
hist_combo2 Dataset: historical data on two single-agents to inform a combination study
hist_combo3 Dataset: historical and concurrent data on a three-way combination
hist_SA Single-agent example
inv_logit Logit (log-odds) and inverse-logit function.
lodds Logit (log-odds) and inverse-logit function.
logit Logit (log-odds) and inverse-logit function.
log_posterior Extract Diagnostic Quantities of 'OncoBayes2' Models
log_posterior.blrmfit Extract Diagnostic Quantities of 'OncoBayes2' Models
neff_ratio Extract Diagnostic Quantities of 'OncoBayes2' Models
neff_ratio.blrmfit Extract Diagnostic Quantities of 'OncoBayes2' Models
nsamples Return the number of posterior samples
nsamples.blrmfit Return the number of posterior samples
nuts_params Extract Diagnostic Quantities of 'OncoBayes2' Models
nuts_params.blrmfit Extract Diagnostic Quantities of 'OncoBayes2' Models
OncoBayes2 OncoBayes2
plot_blrm Plot a fitted model
plot_toxicity_curve Plot a fitted model
plot_toxicity_curve.blrmfit Plot a fitted model
plot_toxicity_curve.blrm_trial Plot a fitted model
plot_toxicity_intervals Plot a fitted model
plot_toxicity_intervals.blrmfit Plot a fitted model
plot_toxicity_intervals.blrm_trial Plot a fitted model
plot_toxicity_intervals_stacked Plot a fitted model
plot_toxicity_intervals_stacked.blrmfit Plot a fitted model
plot_toxicity_intervals_stacked.blrm_trial Plot a fitted model
posterior_interval Posterior intervals
posterior_interval.blrmfit Posterior intervals
posterior_linpred Posterior of linear predictor
posterior_linpred.blrmfit Posterior of linear predictor
posterior_predict Posterior of predictive
posterior_predict.blrmfit Posterior of predictive
predictive_interval Posterior predictive intervals
predictive_interval.blrmfit Posterior predictive intervals
print.blrmfit Bayesian Logistic Regression Model for N-compounds with EXNEX
print.blrm_trial Dose-Escalation Trials guided by Bayesian Logistic Regression Model
prior_summary Summarise model prior
prior_summary.blrmfit Summarise model prior
rhat Extract Diagnostic Quantities of 'OncoBayes2' Models
rhat.blrmfit Extract Diagnostic Quantities of 'OncoBayes2' Models
summary.blrmfit Summarise model results
summary.blrm_trial Summarise trial
update.blrmfit Update data of a BLRM analysis
update.blrm_trial Update data and/or prior of a BLRM trial