Loewe's Additivity


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Documentation for package ‘loewesadditivity’ version 0.1.0

Help Pages

base_GIA Estimate GIA according to the base model
boot_GIA Helper function for the bootstrap results
calc_S Calculate S generally
calc_S_base Calculate S from given tau_1 for base model
cyrpa_ripr CyRPA and RIPR
design_experiment Helper function to generate code to run an experiment
design_grid Function to design an experimental grid of combinations
estimate_GIA Take in dose A and dose B combinations and estimate GIA
estimate_params Estimate the parameters for a given data set and model
fortify_gia_data Put GIA measurements into a dplyr format
get_ed_line Helper function to get the ED50 line
make_grid Make a grid of points
plot_curves Plot the surface and observations
plot_isobologram Plot the estimated isobologram
plot_surface Plot the surface and observations
rh5_ama1ron2 RH5 and AMA1RON2
rh5_rh4 RH5 and RH4
simulate_coverage Simulate a GIA model with an assumed error structure
SSE_GIA Calculate the Sum of Squared Error