An Automated Approach to Evaluating Dose-Effect Experiments Following Litchfield and Wilcoxon (1949)


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Documentation for package ‘LW1949’ version 1.1.0

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LW1949-package Automated Litchfield and Wilcoxon (1949) Evaluation of Dose-Effect Experiments
assessfit Assess Fit of Dose-Response Curve
coefprobit Calculate the Coefficients of a Probit Regression Fit
constrain Constrain Data to a Specified Range
correctval Predict the Corrected Proportional Effect
dataprep Prepare Data
estimable Determine if a Dose-Effect Relation is Estimable
fill Fill in Missing Values
fitHand Best Fit Using Estimated Expected Effects
fitlinear Determine Linear Regression Coefficients from Dose-Effect Data
fitLWauto Best Fit Using Litchfield and Wilcoxon Evaluation of Dose-Effect Experiments
fitprobit Fit a Probit Regression to Dose-Effect Data
fxcat Define Effect Category
gamtable1 Fit a smooth GAM to Table 1 of Litchfield and Wilcoxon (1949)
invprobit Convert Probit Scale to Proportions
keeponly Eliminate Consecutive Extreme Values
LW1949 Automated Litchfield and Wilcoxon (1949) Evaluation of Dose-Effect Experiments
LWchi2 Chi-Squared Statistic
LWestimate Generate Litchfield and Wilcoxon Estimates
LWnomo1 Recreate Litchfield and Wilcoxon's Nomograph No. 1
LWP User Friendly Evaluation of Dose-Effect Experiments using Litchfield-Wilcoxon and Probit Methods
nomoCoord Find the Coordinate from the Scale of a Nomograph
plotDE Plot Dose-Effect Experiments
plotDELP Plot Dose-Effect Experiments
predlinear Determine the Effective Dose from a Linear Regression Fit
predLines Add Litchfield and Wilcoxon Predictions to a Plot
predLinesLP Add Litchfield and Wilcoxon Predictions to a Plot
predprobit Determine the Effective Dose from a Probit Regression Fit
prettylog Pretty Breakpoints on Log Scale
probit Convert Proportions to the Probit Scale
relPotency Relative Potency of Two Toxins