| proteinInteraction {xnet} | R Documentation |
Protein interaction for yeast
Description
A dataset for examining the interaction between proteins of yeast. The dataset consists of the following objects:
Usage
proteinInteraction
Format
proteinInteraction: a numeric square matrix with 150 rows/columns
Kmat_y2h_sc: a numeric square matrix with 150 rows/columns
Details
proteinInteraction: the label matrix based on the protein network taken from the KEGG/PATHWAY database
Kmat_y2h_sc: a kernel matrix indicating similarity of proteins.
The proteins in the dataset are a subset of the 769 proteins used in Yamanishi et al (2004). The kernel matrix used is the combination of 4 kernels: one based on expression data, one on protein interaction data, one on localization data and one on phylogenetic profile. These kernels and their combination are also explained in Yamanishi et al (2004).
Source
https://doi.org/10.1093/bioinformatics/bth910
References
Yamanishi et al, 2004: Protein network inference from multiple genomic data: a supervised approach.