| clean_endPoint_info {toxEval} | R Documentation |
clean_endPoint_info
Description
Define a subset of the ToxCast database for relevance to toxEval analyses. Subsetting is done based upon methods defined by Blackwell et al., 2017 ( doi:10.1021/acs.est.7b01613). Specifically, this function removes endPoints that are ATG sources with signal loss, and NVS with signal gain (basically: some assay/signal combinations are removed because they target non-specific endpoints). Also, this function adds additional categories to intended_target_family and intended_target_family_sub as described in the paper linked above.
Usage
clean_endPoint_info(end_point_info)
Arguments
end_point_info |
Data frame Endpoint information from ToxCast. |
Value
The returned data frame is based on end_point_info, but with some endPoints filtered out and some additional categories in intended_target_family and intended_target_family_sub. The names in intended_target_family are revised to look more appealing in graphs and tables.
Examples
end_point_info <- end_point_info
nrow(end_point_info)
cleaned_ep <- clean_endPoint_info(end_point_info)
nrow(cleaned_ep)