tci_documentation {tci}

tci_documentation

Description

Functions to implement target-controlled infusion algorithms

Details

tci package documentation

This package contains functions to implement target-controlled infusion (TCI) algorithms for compartmental PK models under intravenous administration. TCI algorithms for plasma or effect-site targeting are included and can be extended to pharmacodynamic responses. Custom PK-PD models and custom TCI algorithms can be specified. Functions are provided to simulate responses from PK/PK-PD models under open- or closed-loop control.