pkmod_kim {tci}

Kim population PK model for remifentanil

Description

Evaluate Kim population PK model at patient covariate values. Published in Kim et al. (2017). "Disposition of Remifentanil in Obesity: A New Pharmacokinetic Model Incorporating the Influence of Body Mass" Anesthesiology Vol. 126, 1019–1032. doi: https://doi.org/10.1097/ALN.0000000000001635

Usage

pkmod_kim(AGE, TBW, HGT = NULL, BMI = NULL, MALE = NULL, FFM = NULL, ...)

Arguments

AGE

Age (years)

TBW

Total body weight (kg).

HGT

Height (cm). Used to calculate BMI if BMI is not provided.

BMI

Body mass index. Used to calculate LBM if LBM is not provided.

MALE

Logical. Used to calculate LBM if LBM is not provided.

FFM

Fat-free mass. Can be used instead of BMI and MALE.

...

Arguments passed to 'pkmod'

Value

'pkmod' object with Schnider population PK parameters

Examples

pkmod_kim(AGE = 40,TBW = 75, BMI = 30, MALE = TRUE)
pkmod_kim(AGE = 40,TBW = 75, FFM = 52.83)