sim_meiosis {simcross} | R Documentation |
Simulate meiosis
Description
Output a random meiotic product from an input individual.
Usage
sim_meiosis(parent, m = 10, p = 0, obligate_chiasma = FALSE, Lstar = NULL)
Arguments
parent |
An individual object, as output by
|
m |
interference parameter for chi-square model |
p |
Proportion of chiasmata coming from no-interference process. |
obligate_chiasma |
If TRUE, require an obligate chiasma on the 4-strand bundle at meiosis. |
Lstar |
Adjusted chromosome length, if
|
Details
Simulations are under the Stahl model with the interference parameter being an integer. This is an extension of the chi-square model, but with chiasmata being the superposition of two processes, one following the chi-square model and the other exhibiting no interference.
Value
A list with alleles in chromosome intervals (as integers) and locations of the right endpoints of those intervals.
References
Copenhaver, G. P., Housworth, E. A. and Stahl, F. W. (2002) Crossover interference in arabidopsis. Genetics 160, 1631–1639.
Foss, E., Lande, R., Stahl, F. W. and Steinberg, C. M. (1993) Chiasma interference as a function of genetic distance. Genetics 133, 681–691.
Zhao, H., Speed, T. P. and McPeek, M. S. (1995) Statistical analysis of crossover interference using the chi-square model. Genetics 139, 1045–1056.
See Also
create_parent()
, cross()
,
sim_crossovers()
, calc_Lstar()
Examples
ind <- create_parent(100, 1:2)
prod <- sim_meiosis(ind)