aggr_duplicated_visits |
Aggregate duplicated visits. |
check_df_visit |
Integrity check for df_visit. |
eval_sites |
Evaluate sites. |
eval_sites_deprecated |
Evaluate sites. |
exp_implicit_missing_visits |
Expose implicitly missing visits. |
get_config |
Get Portfolio Configuration |
get_ecd_values |
Get empirical cumulative distribution values of pval or prob_lower |
get_pat_pool_config |
Configure study patient pool by site parameters. |
get_portf_perf |
Get Portfolio Performance |
get_site_mean_ae_dev |
Get site mean ae development. |
get_visit_med75 |
Get visit_med75. |
is_orivisit |
is orivisit class |
is_simaerep |
is simaerep class |
orivisit |
create orivisit object |
pat_aggr |
Aggregate visit to patient level. |
pat_pool |
Create a study specific patient pool for sampling |
plot.simaerep |
plot AE under-reporting simulation results |
plot_dots |
Plots AE per site as dots. |
plot_sim_example |
Plot simulation example. |
plot_sim_examples |
Plot multiple simulation examples. |
plot_study |
Plot ae development of study and sites highlighting at risk sites. |
plot_visit_med75 |
Plot patient visits against visit_med75. |
poiss_test_site_ae_vs_study_ae |
Poisson test for vector with site AEs vs vector with study AEs. |
prep_for_sim |
Prepare data for simulation. |
prob_lower_site_ae_vs_study_ae |
Calculate bootstrapped probability for obtaining a lower site mean AE number. |
purrr_bar |
Execute a purrr or furrr function with a progress bar. |
simaerep |
create simaerep object |
sim_after_prep |
Start simulation after preparation. |
sim_scenario |
simulate single scenario |
sim_sites |
Calculate prob_lower and poisson.test pvalue for study sites. |
sim_studies |
Simulate studies. |
sim_test_data_patient |
simulate patient ae reporting test data |
sim_test_data_portfolio |
Simulate Portfolio Test Data |
sim_test_data_study |
simulate study test data |
sim_ur_scenarios |
Simulate Under-Reporting Scenarios |
site_aggr |
Aggregate from visit to site level. |
with_progress_cnd |
Conditional 'with_progress'. |