sample_LSAE {simDNAmixtures} | R Documentation |
Sample Locus Specific Amplification Efficiency (LSAE) according to prior
Description
Sample Locus Specific Amplification Efficiency (LSAE) according to prior
Usage
sample_LSAE(LSAE_variance, locus_names)
Arguments
LSAE_variance |
Numeric. See gf for an example. |
locus_names |
Character vector. |
Details
In the Bright et al. log normal model, the expected peak height includes a multiplicative factor for the locus (marker). These factors are called the LSAEs (Locus Specific Amplification Efficiencies). In the model, the prior for the log10 of LSAE is normal with mean 0. The variance can be specified.
Value
Named numeric with LSAEs for each locus (names).
Examples
data(gf)
lsae <- sample_LSAE(LSAE_variance = gf$log_normal_settings$LSAE_variance_prior,
locus_names = gf$autosomal_markers)
# the barplot shows that some loci amplify better than others
barplot(lsae, las=2)
[Package simDNAmixtures version 1.0.1 Index]