two_titre_data {sclr}

Simulated two-titre antibody data

Description

A simulated dataset containing 5000 independent observations on antibody titres and the corresponding infection status. The data was simulated to resemble real influenza infection and haemagglutinin + neuraminidase titre data.

Usage

two_titre_data

Format

A data frame with 5000 observations and 3 variables:

logHI

haemagglutinin-inhibiting (HI) titre. True simulated titre on a log scale.

logNI

neuraminidase-inhibiting titre. True simulated titre on a log scale.

status

influenza infection status. 1 - infected. 0 - not infected

Model

The model behind the simulation was

\lambda * (1 - f(\beta_0 + \beta_1 * HI + \beta_2 * NI))

Where

• f - Inverse logit function

• \lambda = 0.5

• \beta_0 = -7.5

• \beta_1 = 2

• \beta_2 = 2