colon_lev {rmt} | R Documentation |
A dataset from a landmark colon cancer trial
Description
A landmark colon cancer trial on the efficacy of levamisole and fluorouracil was reported by Moertel et al. (1990). The trial recruited 929 patients with stage C disease and randomly assigned them to levamisole treatment alone, levamisole combined with fluorouracil, and the control. The dataset here is restricted to the comparison between the combined treatment and control groups, consisting of 304 and 314 patients, respectively.
Usage
colon_lev
Format
A data frame with 915 rows and 6 variables:
- id
Unique patient ID.
- time
Event time (years).
- status
Event type; 1 = cancer relapse, 2 = death.
- rx
"Lev+5FU" = combined treatment, "Control" = control.
- age
Patient age (years) at randomization.
- sex
0 = female, 1 = male.
References
MOERTEL, C. G., FLEMING, T. R., MACDONALD, J. S., HALLER, D. G., LAURIE, J. A., GOODMAN, P. J., UNGERLEIDER, J. S., EMERSON, W. A., TORMEY, D. C., GLICK, J. H. et al. (1990). Levamisole and fluorouracil for adjuvant therapy of resected colon carcinoma. New Engl. J. Med. 322, 352–358.