chenPar {randomizeR} | R Documentation |
Representing Chen's Design
Description
Represents the randomization procedure Chen's Design.
Usage
chenPar(N, mti = N, p = 0.5, groups = LETTERS[1:2])
Arguments
N |
integer for the total sample size of the trial. |
mti |
maximum tolerated imbalance in patient numbers during the trial. |
p |
success probability of the biased coin (e.g. in Efron's Biased Coin Design). |
groups |
character vector of labels for the different treatments. |
Details
Flip a biased coin with probability p
in favor of the treatment
which is allocated less frequently as long as the difference in group sizes does
not exceed the mti
. If the mti
is reached a deterministic
allocation is done, so that the difference in group sizes is reduced.
If both treatments have been assigned equally often a fair coin is tossed.
Value
S4
object of the class chenPar
.
References
Chen Yung-Pin (1999) Biased coin design with imbalance tolerance. Comm. in Stat., 15, 953-975.
See Also
Other randomization procedures:
abcdPar
,
bbcdPar
,
bsdPar
,
crPar
,
createParam()
,
ebcPar
,
gbcdPar
,
hadaPar
,
mpPar
,
pbrPar
,
rarPar
,
rpbrPar
,
rtbdPar
,
tbdPar
,
udPar