sim.als {rCNV}

Simulate Allele Frequencies

Description

This function simulates allele frequencies of a desired population size under HWE

Usage

sim.als(n = 500, nrun = 10000, res = 0.001, plot = TRUE)

Arguments

n

desired populations size (set this value same as your actual population size for an accurate simulation)

nrun

number of simulations to run on each allele frequency. The higher this number, the closer the simulations will be to the theoretical values (at the cost of computer power); 10000 is an optimal value.

res

desired resolution of the theoretical allele frequency

plot

logical. whether to plot the simulation

Value

A list of two matrices:

1. allele_freqs: theoretical allele frequency

2. simulated_freqs: simulated frequencies at different confidence intervals

Author(s)

Piyal Karunarathne, Pascal Milesi

Examples

## Not run: alleles <- sim.als(n=200,nrun=1000,res=0.001,plot=TRUE)