Evaluate Partitioned Survival and State Transition Models


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Documentation for package ‘psm3mkv’ version 0.3.2

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calc_allrmds Calculate restricted mean durations for each health state and all three models
calc_haz_psm Derive pre and post-progression hazards of death under PSM
calc_likes Calculate likelihoods for three three-state model structures
calc_rmd Calculate restricted mean durations
calc_surv_psmpps Derive PPS survival function under a PSM
check_consistent_pfs Check consistency of PFS definition Check that PFS is defined consistently with TTP and OS in a dataset. This convenience function compares 'pfs.durn' with the lower of 'ttp.durn' and 'os.durn', and checks that the event field 'pfs.flag' is consistent with 'ttp.flag' and 'os.flag' (is 1 when either 'ttp.flag' or 'os.flag' is one).
compare_psm_likes Compare likelihoods of PSMs
constrain_survprob Constrain survival probabilities according to hazards in a lifetable Recalculated constrained survival probabilities (by week) as the lower of the original unadjusted survival probability and the survival implied by the given lifetable (assumed indexed as years).
create_dummydata Create dummy dataset for illustration
create_extrafields Create the additional time-to-event endpoints, adjusting for cutpoint
find_bestfit Find the "best" survival regression from a list of model fits
fit_ends_mods_par Fit multiple parametric survival regressions to the multiple required endpoints
fit_ends_mods_spl Fit multiple spline regressions to the multiple required endpoints
graph_psm_hazards Graph the PSM hazard functions
graph_psm_survs Graph the PSM survival functions
graph_survs Graph the observed and fitted state membership probabilities
prob_os_psm Calculate probability of being alive in a partitioned survival model
prob_os_stm_cf Calculate probability of being alive under the state transition clock forward model
prob_os_stm_cr Calculate probability of being alive under the state transition clock reset model
prob_pd_psm Calculate membership probability of progressed disease state in a partitioned survival model
prob_pd_stm_cf Calculate probability of having progressed disease under the state transition clock forward model
prob_pd_stm_cr Calculate probability of having progressed disease under the state transition clock reset model
prob_pf_psm Calculate probability of being progression free in partitioned survival model
prob_pf_stm Calculate probability of being progression free in either state transition model (clock forward or clock reset)
prob_pps_cf Calculate probability of post progression survival under the state transition clock forward model
prob_pps_cr Calculate probability of post progression survival under the state transition clock reset model
vlookup VLOOKUP function