ind_stdcontinuous {polypharmacy}

Assess polypharmacy based on the number of medications that is consumed both during the initial and the final period of the study period

Description

Calculates the number of distinct medications that are consumed both during the initial and the final period of the overall study period by every individual of the study cohort and provides cohort descriptive statistics on this indicator.

Usage

ind_stdcontinuous(
  processed_tab,
  pdays,
  stats = c("mean", "sd", "min", "p5", "p10", "p25", "median", "p75", "p90", "p95",
    "max")
)

Arguments

processed_tab

Table of individual drug treatments over the study period. Created by data_process function.

pdays

Duration (in days) of the initial and final periods of time . The initial period = [min; min+pdays] and the final period = [max-pdays; max], where min and max are the study_start and study_end arguments. See data_process.

stats

Cohort descriptive statistics to calculate on the polypharmacy indicator. See Details for possible values.

Details

stats: Possible values are

• 'mean', 'min', 'median', 'max', 'sd';

• 'pX' where X is an integer value in ]0, 100];

• 'q1'='p25', 'q2'='p50'='median', q3='p75'.

Value

list:

• indic: data.table indicating each stats (columns).

• stats_id: data.table indicating the number of drugs use for each individual (all cohort).

Examples

rx1 <- data.frame(id = c(1, 1, 1, 2, 3),
                  code = c("A", "A", "B", "A", "A"),
                  date = c("2000-01-01", "2000-01-22", "2000-01-10", "2000-01-01", "2000-01-20"),
                  duration = c(10, 10, 22, 31, 12))
cohort1 <- data.frame(id = as.numeric(1:4),
                      age = c(45, 12, 89, 31),
                      sex = c("F", "F", "M", "M"))
rx_proc1 <- data_process(Rx_deliv = rx1, Rx_id = "id", Rx_drug_code = "code",
                         Rx_drug_deliv = "date", Rx_deliv_dur = "duration",
                         Cohort = cohort1, Cohort_id = "id",
                         study_start = "2000-01-01", study_end = "2000-01-31",
                         cores = 1)
dt_ind_stdcontinuous <- ind_stdcontinuous(processed_tab = rx_proc1, pdays = 10)