eff {phase1PRMD} | R Documentation |
Efficacy response generation parameters
Description
A list of 4 records the parameters for efficacy measure generation. This
serves as an example of the parameter settings for efficacy measure
generation in function SimPRMD
. Check eff_summary
or
SimPRMD
to see the examples of using dataset eff
in
generating efficacy measure.
Usage
eff
Format
An object of class list
of length 4.
Value
Dose_Cycle_Meff |
Dose-cycle mean efficacy matrix. An array of 4 dimension providing the mean of the multivariate Gaussian distribution in efficacy data generation. The dimension of the Dose-cycle mean efficacy matrix is 5 5 6 6 which represents dose efficacy pattern, cycle efficacy pattern, dose and cycle. Patterns are ordered in a way that the first is increasing, the second is flat, the third is platform, the fourth is decreasing, and the fifth is quadratic efficacy across dose levels and cycles. |
Sigma |
A 6 by 6 matrix, the covariance matrix of the multivariate Guassian distribution in efficacy data generation. |
sd_trans |
A positive number controls the skewness of the distribution of the efficacy response |
eff.M |
An array recording the corresponding mean of the generated
efficacy data with parameters specified by |