Personalized Repeated Measurement Design for Phase I Clinical Trials


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Documentation for package ‘phase1PRMD’ version 1.0.2

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eff Efficacy response generation parameters
eff_suggest Suggest the input 'eff.structure' of function 'SimPRMD' with selected 'eff.sd_tran'
eff_summary Compute the summary statistics of efficacy measure with specified parameters.
nTTP.array Generate the nTTP dictionary
nTTP_summary Generate the mean nTTP score and the probability of observing DLT for all doses and cycles
patlist.display Display patient records
patlist_sim A list of patient information
plot.RunPRMD Plot nTTP and efficacy boxplots of a RunPRMD object
plot.SimPRMD Plots of a SimPRMD object
print.summary.RunPRMD Displays a useful description of a summary.RunPRMD object
print.summary.SimPRMD Displays a useful description of a summary.SimPRMD object
prob Toxicity probability matrix
RunPRMD Implement a Multi-Stage Phase I Dose-Finding Design to recommend dosage selection based on the data collected in the available patient cohorts
SimPRMD Simulation for a Multi-Stage Phase I Dose-Finding Design
summary.RunPRMD Summary a RunPRMD object
summary.SimPRMD Summary a SimPRMD object