| dominant {paramlink} | R Documentation |
Example pedigree for linkage analysis
Description
Medical pedigree with 23 individuals of which 15 are genotyped with 650 SNP markers. Eleven family members are affected by a disease, showing an autosomal dominant inheritance pattern.
Usage
dominant
Format
A data frame with 23 rows and 1306 columns, describing the pedigree and marker data in pre-makeped format. The first 6 columns contain the pedigree structure and affection status, while the final 1300 columns hold the marker alleles.
FAMID. Family ID
ID. Individual ID
FID. Father ID
MID. Mother ID
SEX. Gender (male=1, female=2)
AFF. Affection status (unaffected=1, affected=2, unknown=0)
M1_1. First allele of marker 1
M1_2. Second allele of marker 1
...
M650_1. First allele of marker 650
M650_2. Second allele of marker 650
All markers are SNPs, whose alleles are written as 1 and 2. Missing alleles are denoted by 0.
Examples
x = linkdat(dominant)
summary(x)