Dogliotti2014 {netmeta}

Network meta-analysis of antithrombotic treatments in patients with non-valvular atrial fibrillation

Description

This data set comes from a systematic review aiming to determine the effects of eight antithrombotic treatments in reducing the incidence of major thrombotic events in patients with non-valvular atrial fibrillation (Dogliotti et al., 2014). The review included 20 studies (79,808 participants), four of which were three-arm studies. The primary outcome is stroke reduction.

Format

A data frame with the following columns:

study	study label
id	study ID
treatment	treatment
stroke	number of strokes
total	number of individuals in treatment arm

Source

Dogliotti A, Paolasso E, Giugliano RP (2014): Current and new oral antithrombotics in non-valvular atrial fibrillation: a network meta-analysis of 79 808 patients. Heart, 100, 396–405

See Also

pairwise, metabin, netmetabin

Examples

data(Dogliotti2014)
Dogliotti2014

## Not run: 
# Transform data from long arm-based format to contrast-based
# format. Argument 'sm' has to be used for odds ratio as summary
# measure; by default the risk ratio is used in the metabin
# function called internally.
#
p1 <- pairwise(treatment, stroke, total, studlab = study,
  data = Dogliotti2014, sm = "OR")

# Conduct Mantel-Haenszel network meta-analysis
#
netmetabin(p1, ref = "plac")

## End(Not run)