ABH_pi0_est {mutoss} | R Documentation |
Lowest Slope Line (LSL) method of Hochberg and Benjamini for estimating pi0
Description
The Lowest Slope Line (LSL) method of Hochberg and Benjamini for estimating pi0 is applied to pValues. This method for estimating pi0 is motivated by the graphical approach proposed by Schweder and Spjotvoll (1982), as developed and presented in Hochberg and Benjamini (1990).
Usage
ABH_pi0_est(pValues)
Arguments
pValues |
The raw p-values for the marginal test problems |
Value
pi0.ABH |
The estimated proportion of true null hypotheses. |
Author(s)
WerftWiebke
References
Hochberg, Y. and Benjamini, Y. (1990). More powerful procedures for multiple significance testing. Statistics in Medicine 9, 811-818.
Schweder, T. and Spjotvoll, E. (1982). Plots of P-values to evaluate many tests simultaneously. Biometrika 69, 3, 493-502.
Examples
my.pvals <- c(runif(50), runif(50, 0, 0.01))
result <- ABH_pi0_est(my.pvals)
[Package mutoss version 0.1-13 Index]