Monitoring Overall Survival in Pivotal Trials in Indolent Cancers


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Documentation for package ‘monitOS’ version 0.1.5

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app_server Shiny app server
app_ui Shiny app UI
bounds Bounds
calc_posterior Function which calculates for k=1, ..., K, Pr(log-HR >= lhr_null | theta.hat.k = lhr_con.k) i.e. the posterior probability the true OS log-hr exceeds the minimum unacceptable OS log-HR given the estimate of the log-hr at analysis k equals lhr_con.k (i.e. the estimate is equal to the stage k 'continuation threshold').
calc_predictive Title"
meeting_probs Probabilities of meeting positivity threshold under target HR
run_app monitOS app