random_OR {metagear} | R Documentation |
Random generation of odds ratio (OR) effect sizes.
Description
Generates random odds ratios, logged odds ratios, and their variances (Cornfield 1951).
Usage
random_OR(K, p_A, N_A, p_B, N_B, continuity = 0.5, logged = TRUE)
Arguments
K |
Number of effect sizes to generate. |
p_A |
The odds of the event of interest for Group A. A probability ranging from zero to one. |
N_A |
The total number of samples of Group A. |
p_B |
The odds of the event of interest for Group B. A probability ranging from zero to one. |
N_B |
The total number of samples of Group B. |
continuity |
Odds ratios with zero events cannot be computed. Following, Cox (1970), a continuity correction can be added to each cell of the 2 by 2 table to help improve this problem of zero events within the table. The default value added is 0.5. |
logged |
When |
Value
A data table with columns of random effect sizes (OR) and their variances.
References
Cornfield, J. 1951. A method for estimating comparative rates from Clinical Data. Applications to cancer of the lung, breast, and cervix. Journal of the National Cancer Institute 11: 1269-1275.
Cox, D.R. 1970. The continuity correction. Biometrika 57: 217-219.
Examples
random_OR(K = 5, p_A = 0.3, N_A = 100, p_B = 0.1, N_B = 60)