median_polish {iq}

A wrapper for the R implementation of the median polish algorithm

Description

Estimates protein abundances using the Tukey median polish algorithm.

Usage

median_polish(X)

Arguments

X

A matrix of ion intensities in log2 space. Columns are samples and rows are fragment ions.

Value

A list of two components is returned

estimate

A vector with length equal to the number of columns of the input containing the protein abundances in log2 space.

annotation

Reserved, currently an empty string

Author(s)

Thang V. Pham

References

Pham TV, Henneman AA, Jimenez CR. iq: an R package to estimate relative protein abundances from ion quantification in DIA-MS-based proteomics. Bioinformatics 2020 Apr 15;36(8):2611-2613.

Tukey JW. Exploratory Data Analysis, Reading Massachusetts: Addison-Wesley, 1977.