fast_preprocess {iq} | R Documentation |
Data filtering and normalization
Description
Filters out low intensities and performs median normalization.
Usage
fast_preprocess(quant_table,
median_normalization = TRUE,
log2_intensity_cutoff = 0,
pdf_out = "qc-plots-fast.pdf",
pdf_width = 12,
pdf_height = 8,
show_boxplot = TRUE)
Arguments
quant_table |
The |
median_normalization |
A logical value. The default |
log2_intensity_cutoff |
Entries lower than this value in log2 space are ignored. Plot a histogram of all intensities to set this parameter. |
pdf_out |
A character string specifying the name of the PDF output. A |
pdf_width |
Width of the pdf output in inches. |
pdf_height |
Height of the pdf output in inches. |
show_boxplot |
A logical value. The default |
Value
A list is returned with the same components as input data in which low intensities are filtered out and median normalization is performed if requested.
Author(s)
Thang V. Pham
References
Pham TV, Henneman AA, Jimenez CR. iq: an R package to estimate relative protein abundances from ion quantification in DIA-MS-based proteomics. Bioinformatics 2020 Apr 15;36(8):2611-2613.