get_wetmore_cheminfo {httk} | R Documentation |
Get literature Chemical Information. (deprecated).
Description
This function is included for backward compatibility. It calls
get_lit_cheminfo
which
provides the information specified in "info=" for all
chemicals with data from the Wetmore et al. (2012) and (2013) publications
and other literature.
Usage
get_wetmore_cheminfo(
info = "CAS",
species = "Human",
suppress.messages = FALSE
)
Arguments
info |
A single character vector (or collection of character vectors) from "Compound", "CAS", "MW", "Raw.Experimental.Percentage.Unbound", "Entered.Experimental.Percentage.Unbound", "Fub", "source_PPB", "Renal_Clearance", "Met_Stab", "Met_Stab_entered", "r2", "p.val", "Concentration..uM.", "Css_lower_5th_perc.mg.L.", "Css_median_perc.mg.L.", "Css_upper_95th_perc.mg.L.", "Css_lower_5th_perc.uM.","Css_median_perc.uM.","Css_upper_95th_perc.uM.", and "Species". |
species |
Species desired (either "Rat" or default "Human"). |
suppress.messages |
Whether or not the output message is suppressed. |
Value
info |
Table/vector containing values specified in "info" for valid chemicals. |
Author(s)
John Wambaugh
References
Wetmore, B.A., Wambaugh, J.F., Ferguson, S.S., Sochaski, M.A., Rotroff, D.M., Freeman, K., Clewell, H.J., Dix, D.H., Andersen, M.E., Houck, K.A., Allen, B., Judson, R.S., Sing, R., Kavlock, R.J., Richard, A.M., and Thomas, R.S., "Integration of Dosimetry, Exposure and High-Throughput Screening Data in Chemical Toxicity Assessment," Toxicological Sciences 125 157-174 (2012)
Wetmore, B.A., Wambaugh, J.F., Ferguson, S.S., Li, L., Clewell, H.J. III, Judson, R.S., Freeman, K., Bao, W, Sochaski, M.A., Chu T.-M., Black, M.B., Healy, E, Allen, B., Andersen M.E., Wolfinger, R.D., and Thomas R.S., "The Relative Impact of Incorporating Pharmacokinetics on Predicting in vivo Hazard and Mode-of-Action from High-Throughput in vitro Toxicity Assays" Toxicological Sciences, 132:327-346 (2013).
Wetmore, B. A., Wambaugh, J. F., Allen, B., Ferguson, S. S., Sochaski, M. A., Setzer, R. W., Houck, K. A., Strope, C. L., Cantwell, K., Judson, R. S., LeCluyse, E., Clewell, H.J. III, Thomas, R.S., and Andersen, M. E. (2015). "Incorporating High-Throughput Exposure Predictions with Dosimetry-Adjusted In Vitro Bioactivity to Inform Chemical Toxicity Testing" Toxicological Sciences, kfv171.
Examples
get_lit_cheminfo()
get_lit_cheminfo(info=c('CAS','MW'))