get_caco2 {httk}

Retrieve in vitro measured Caco-2 membrane permeabilit

Description

This function checks for chemical-specific in vitro measurements of the Caco-2 membrane permeability in the chem.physical_and_invitro.data table. If no value is available argument Caco2.Pab.default is returned.

Usage

get_caco2(
  chem.cas = NULL,
  chem.name = NULL,
  dtxsid = NULL,
  Caco2.Pab.default = 1.6,
  suppress.messages = FALSE
)

Arguments

chem.cas

Chemical Abstract Services Registry Number (CAS-RN) – the chemical must be identified by either CAS, name, or DTXISD

chem.name

Chemical name (spaces and capitalization ignored) – the chemical must be identified by either CAS, name, or DTXISD

dtxsid

EPA's DSSTox Structure ID (https://comptox.epa.gov/dashboard) – the chemical must be identified by either CAS, name, or DTXSIDs

Caco2.Pab.default

sets the default value for Caco2.Pab if Caco2.Pab is unavailable.

suppress.messages

Whether or not the output message is suppressed.

Author(s)

John Wambaugh