estimate_hematocrit {httk}

Generate hematocrit values for a virtual population

Description

Predict hematocrit from age using smoothing splines and kernel density estimates of residual variability fitted to NHANES data, for a given combination of gender and NHANES race/ethnicity category.

Usage

estimate_hematocrit(gender, reth, age_years, age_months, nhanes_mec_svy)

Arguments

gender

Gender for which to generate hematocrit values ("Male" or "Female")

reth

NHANES race/ethnicity category for which to generate serum creatinine values ("Mexican American", "Non-Hispanic Black", "Non-Hispanic White", "Other", or "Other Hispanic")

age_years

Vector of ages in years for individuals for whom to generate hematocrit values (corresponding to age_months)

age_months

vector of ages in months for individuals for whom to generate hematocrit values (between 0-959 months)

nhanes_mec_svy

surveydesign object created from mecdt using svydesign (this is done in httkpop_generate)

Details

This function should usually not be called directly by the user. It is used by httkpop_generate() in "virtual-individuals" mode, after drawing gender, NHANES race/ethnicity category, and age from their NHANES proportions/distributions.

Value

A vector of numeric generated hematocrit values (blood percentage red blood cells by volume).

Author(s)

Caroline Ring

References

Ring CL, Pearce RG, Setzer RW, Wetmore BA, Wambaugh JF (2017). “Identifying populations sensitive to environmental chemicals by simulating toxicokinetic variability.” Environment International, 106, 105–118.