estimate_gfr {httk}

Predict GFR.

Description

Predict GFR using CKD-EPI equation (for adults) or BSA-based equation (for children).

Usage

estimate_gfr(gfrtmp.dt, gfr_resid_var = TRUE, ckd_epi_race_coeff = FALSE)

Arguments

gfrtmp.dt

A data.table with columns gender, reth, age_years, age_months, BSA_adj, serum_creat.

gfr_resid_var

Logical value indicating whether or not to include residual variability when generating GFR values. (Default is TRUE.)

ckd_epi_race_coeff

Logical value indicating whether or not to use the "race coefficient" from the CKD-EPI equation when estimating GFR values. (Default is FALSE.)

Details

Add residual variability based on reported residuals for each equation.

Value

The same data.table with a gfr_est column added, containing estimated GFR values.

Author(s)

Caroline Ring

References

Ring CL, Pearce RG, Setzer RW, Wetmore BA, Wambaugh JF (2017). “Identifying populations sensitive to environmental chemicals by simulating toxicokinetic variability.” Environment International, 106, 105–118.