TransformSnapshot {grandR}

Estimate parameters for a one-shot experiment.

Description

Under steady state conditions it is straight-forward to estimate s and d. Otherwise, the total levels at some other time point are needed.

Usage

TransformSnapshot(ntr, total, t, t0 = NULL, f0 = NULL, full.return = FALSE)

Arguments

ntr

the new to total RNA ratio (measured)

total

the total level of RNA (measured)

t

the labeling duration

t0

time before measurement at which f0 is total level (only necessary under non-steady-state conditions)

f0

total level at t0 (only necessary under non-steady-state conditions)

full.return

also return the provided parameters

Details

t0 must be given as the total time in between the measurement of f0 and the given ntr and total values!

Value

a named vector for s and d