| ComputePseudoNtr {grandR} | R Documentation |
Compute pseudo NTRs from two count matrices
Description
NTRs can be computed from given new and total counts.
Usage
ComputePseudoNtr(
data,
new.slot,
total.slot = DefaultSlot(data),
detection.rate = 1
)
Arguments
data |
a grandR object |
new.slot |
the slot containing new RNA counts |
total.slot |
the slot containing total RNA counts |
detection.rate |
the detection rate of T-to-C mismatch reads (see details) |
Details
To correct for some bias, a detection rate (as suggested by Cao et al., Nature Biotech 2020) should be provided. This detection rate defines, how much new RNA is detected on average using the T-to-C mismatch reads.
Value
a new grandR object
[Package grandR version 0.2.5 Index]