liver {glmtoolbox}

Liver cancer in mice

Description

Female mice were continuously fed dietary concentrations of 2-Acetylaminofluorene (2-AAF), a carcinogenic and mutagenic derivative of fluorene. Serially sacrificed, dead or moribund mice were examined for tumors and deaths dates recorded. These data consist of the incidences of liver neoplasms in mice observed during 18 months.

Usage

data(liver)

Format

A data frame with 8 rows and 3 variables:

dose

a numeric vector giving the dose, in parts per 10^4, of 2-AAF.

exposed

a numeric vector giving the number of mice exposed to each dose of 2-AAF.

cancer

a numeric vector giving the number of mice with liver cancer for each dose of 2-AAF.

References

Zhang H., Zelterman D. (1999) Binary Regression for Risks in Excess of Subject-Specific Thresholds. Biometrics 55:1247-1251.

See Also

bladder

Examples

data(liver)
dev.new()
barplot(100*cancer/exposed ~ dose, beside=TRUE, data=liver, col="red",
        xlab="Dose of 2-AAF", ylab="% of mice with liver cancer")