pfc.sim {gap}R Documentation

Probability of familial clustering of disease

Description

Probability of familial clustering of disease

Usage

pfc.sim(famdata, n.sim = 1e+06, n.loop = 1)

Arguments

famdata

collective information of sib size, number of affected sibs and their frequencies.

n.sim

number of simulations in a single Monte Carlo run.

n.loop

total number of Monte Carlo runs.

Details

To calculate probability of familial clustering of disease using Monte Carlo simulation.

Value

The returned value is a list containing:

Note

Adapted from runi.for from Change Yu, 5/6/4

Author(s)

Chang Yu, Dani Zelterman

References

Yu C, Zelterman D (2001). “Exact inference for family disease clusters.” Communications in Statistics - Theory and Methods, 30(11), 2293-2305. ISSN 0361-0926, doi:10.1081/STA-100107686.

See Also

pfc

Examples

## Not run: 
# Li FP, Fraumeni JF Jr, Mulvihill JJ, Blattner WA, Dreyfus MG, Tucker MA,
# Miller RW. A cancer family syndrome in twenty-four kindreds.
# Cancer Res 1988, 48(18):5358-62. 

# family_size  #_of_affected frequency

famtest<-c(
1, 0, 2,
1, 1, 0,
2, 0, 1,
2, 1, 4,
2, 2, 3,
3, 0, 0,
3, 1, 2,
3, 2, 1,
3, 3, 1,
4, 0, 0,
4, 1, 2,
5, 0, 0,
5, 1, 1,
6, 0, 0,
6, 1, 1,
7, 0, 0,
7, 1, 1,
8, 0, 0,
8, 1, 1,
8, 2, 1,
8, 3, 1,
9, 3, 1)

test<-matrix(famtest,byrow=T,ncol=3)

famp<-pfc.sim(test)

## End(Not run)


[Package gap version 1.5-3 Index]