A Generalized Joint Location and Scale Framework for Association Testing


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Documentation for package ‘gJLS2’ version 0.2.0

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chrXdat X-chromosomal example using the 1000 Genomes Project data
gJLS2 A Generalized Joint-Location-Scale (gJLS) Test
gJLS2s generalized Joint-Location-Scale (gJLS) test with summary statistics
leveneRegA_per_SNP The generalized Levene's test via a two-stage regression for variance homogeneity by SNP genotype (autosomes)
leveneRegX_per_SNP Levene's regression tests for variance homogeneity by SNP genotype (X-chromosome specific)
leveneTests_per_SNP Levene's test for variance homogeneity by SNP genotypes (sex-specific p-values)
locReg Location (mean-based association) test
scaleReg Scale (variance-based association) test