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Delirium in critically ill ICU patients dataset: the REDUCE clinical trial
Description
This dataset contains an extract of 500 randomly selected patients from the randomized, double-blind, placebo-controlled REDUCE trial for critically ill patient admited to ICU. This trial investigated whether Haloperidol (1 or 2 mg) administered as a prophylactic improved 28-day survival compared to placebo. Recurrent episodes of delirium are recorded and patients and patients can be censored by death or discharge from the ICU.
Usage
data(reduce)
Format
This data frame contains the following columns:
- id
Identification number of a patient
- t.start
Start time of the interval (0 or time of last recurrence)
- t.stop
Stop time of the interval, either delirium recurrence time or censoring time.
- del
Delirium status
- death
Death status
- discharge
Discharge status
- treatment
Treatment indicator, 1 if patient was randomized to receive 2mg of Haloperidol, 0 for control
Source
Van Den Boogaard, M., Slooter, A. J., Bruggemann, R. J., Schoonhoven, L., Beishuizen, A., Vermeijden, J. W., et al. (2018). Effect of haloperidol on survival among critically ill adults with a high risk of delirium: the REDUCE randomized clinical trial. Jama, 319(7), 680-690.