gastadj {frailtypack} | R Documentation |
Advanced Gastric Cancer dataset
Description
This meta-analysis was carried out by the GASTRIC (Global Advanced/Adjuvant Stomach Tumor Research international Collaboration) group, using individual data on patients with curatively resected gastric cancer. Data from all published randomized trials, with a patient recruitment end date before 2004, and comparing adjuvant chemotherapy with surgery alone for resectable gastric cancers, were searched electronically. The candidate surrogate endpoint S was Desease-free survival time, defined as the time (in days) to relapse, second cancer or dead from any cause. The true endpoint T was the overall survival time, defined as the time (in days) from randomization to death of any cause or to the last follow-up.
Usage
data(gastadj)
Format
This data frame contains the following columns:
- trialID
The trial in which the patient was treated
- patientID
The identification number of a patient
- trt
The treatment indicator, coded as 0 = Control and 1 = Experimental
- timeS
The candidate surrogate (progression-free survival in days)
- statusS
Censoring indicator for for Progression-free survival (0 = alive and progression-free, 1 = with progression or dead)
- timeT
The true endpoint (overall survival time in days)
- statusT
Censoring indicator for survival time (0 = alive, 1 = dead)
Source
Oba K, Paoletti X, Alberts S, Bang YJ, Benedetti J, Bleiberg H, Catalona P, Lordick F, Michiels S, Morita A, Okashi Y, Pignon JP, Rougier P, Sasako M, Sakamoto J, Sargent D, Shitara K, Van Cutsem E, Buyse M, Burzykowski T on behalf of the GASTRIC group (2013). Disease-Free Survival as a Surrogate for Overall Survival in Adjuvant Trials of Gastric Cancer: A Meta-Analysis. JNCI: Journal of the National Cancer Institute;105(21):1600-1607