| epilepsy {faraway} | R Documentation |
Epileptic seizures in clinical trial of drug
Description
Data from a clinical trial of 59 epileptics. For a baseline, patients were observed for 8 weeks and the number of seizures recorded. The patients were then randomized to treatment by the drug Progabide (31 patients) or to the placebo group (28 patients). They were observed for four 2-week periods and the number of seizures recorded.
Format
A data frame with 295 observations on the following 6 variables.
- seizures
number of seizures
- id
identifying number
- treat
1=treated, 0=not
- expind
0=baseline period, 1=treatment period
- timeadj
weeks of period
- age
in years
Source
Thall, P. F. and S. C. Vail (1990). Some covariance models for longitudinal count data with overdispersion. Biometrics 46, 657-671.
References
Breslow, N. E. and D. G. Clayton (1993). Approximate inference in generalized linear mixed models. Journal of the American Statistical Association 88, 9-25. Diggle, P. J., P. Heagerty, K. Y. Liang, and S. L. Zeger (2002). Analysis of Longitudinal Data (2 ed.). Oxford: Oxford University Press.
Examples
data(epilepsy)
## maybe str(epilepsy) ; plot(epilepsy) ...