exp1 {expirest}

Stability potency data of five batches

Description

A data set containing the potency stability data (in % of label claim (LC)) of five batches of a drug product obtained over a 24 months period. A total of n = 53 independent measurements are available (corresponding to data shown in Tables IV, VI and VIII in LeBlond et al. (2011)). Data in Table IV (batches b2, b5 and b7) are compatible with a common intercept / common slope (cics) model, data in Table VI (batches b3, b4 and b5) with a different intercept / common slope (dics) model and data in Table VIII (bathes b4, b5 and b8) with a different intercept / different slope (dids) model.

Usage

data(exp1)

Format

A data frame with 53 observations and 3 variables:

Batch

Factor with levels b2, b3, b4, b5, b7 and b8

Month

Numeric representing the time points of testing from the start (0 months) to the end (24 months) of the study.

Potency

Numeric of the measured potency values in %LC

Source

See reference: Example data sets shown in Tables IV, VI and VIII.

References

LeBlond, D., Griffith, D. and Aubuchon, K. Linear Regression 102: Stability Shelf Life Estimation Using Analysis of Covariance. J Valid Technol (2011) 17(3): 47-68.

Examples

str(exp1)