piecewiseExp_MLE {eventTrack}R Documentation

Estimate hazard function in piecewise Exponential survival model

Description

This function estimates the values of the hazard function and the change points in a piecewise Exponential survival model. The number of change points K needs to be pre-specified.

Usage

piecewiseExp_MLE(time, event, K)

Arguments

time

Event times, censored or observed, in months.

event

Censoring indicator, 1 for event, 0 for censored.

K

Number of change points to be used in the model.

Value

A list containing the following objects:

tau

The maximum likelihood estimates of the change points.

lambda

The maximum likelihood estimates of the value of the hazard function.

lambda.SE

The standard errors of lambda.

K

Number of change points to be used in the model.

Author(s)

Kaspar Rufibach (maintainer)
kaspar.rufibach@roche.com

References

Fang, L., Zheng, S. (2011). A hybrid approach to predicting events in clinical trials with time-to-event outcomes. Contemp. Clin. Trials, 32, 755–759.

Goodman, M.S., Li, Y., Tiwari, R.C. (2011). Detecting multiple change points in piecewise constant hazard functions. J. Appl. Stat, 38(11), 2523–2532.

Examples

# see vignette

[Package eventTrack version 1.0.3 Index]