AED3_SSR.boundary {esDesign} | R Documentation |
Calculate the futility and efficacy stopping boundaries in Adaptive enrichment design (Strategy 3) with Sample Size Re-estimation Procedure for the continuous endpoint
Description
The AED3_SSR.boundary()
is used to calculate the futility
and efficacy stopping boundaries in the Adaptive Enrichment Design with
Sample Size Re-estimation Procedure.
Usage
AED3_SSR.boundary(rho, alpha, pstar)
Arguments
rho |
The proportion of subgroup 1 |
alpha |
The overall Type I error rate |
pstar |
The |
Value
A list contains
upper.boundary The upper or the efficacy stopping boundary
lower.boundary The lower or the futility stopping boundary
Examples
rho <- 0.5
alpha <- 0.05
pstar <- 0.15
res <- AED3_SSR.boundary(rho = rho, alpha = alpha, pstar = pstar)
[Package esDesign version 1.0.3 Index]