AED3_SSR.boundary {esDesign}R Documentation

Calculate the futility and efficacy stopping boundaries in Adaptive enrichment design (Strategy 3) with Sample Size Re-estimation Procedure for the continuous endpoint

Description

The AED3_SSR.boundary() is used to calculate the futility and efficacy stopping boundaries in the Adaptive Enrichment Design with Sample Size Re-estimation Procedure.

Usage

AED3_SSR.boundary(rho, alpha, pstar)

Arguments

rho

The proportion of subgroup 1

alpha

The overall Type I error rate

pstar

The (1 - power) of accepting the null hypothesis at the interim analysis.

Value

A list contains

Examples

rho <- 0.5
alpha <- 0.05
pstar <- 0.15
res <- AED3_SSR.boundary(rho = rho, alpha = alpha, pstar = pstar)

[Package esDesign version 1.0.3 Index]